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pentobarbital will lessen the level or effect of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will minimize the extent or outcome of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases levels of toremifene by affecting hepatic/intestinal enz